Antibody-enhanced hepatitis E virus nanofiltration in the course of the manufacture of human immunoglobulin
Background: Circulation of hepatitis E virus (HEV) in areas the place plasma is sourced for the manufacture of plasma-derived medicinal merchandise (PDMPs) has prompted verification of HEV clearance. HEV exists as quasi lipid-enveloped (LE) and non-lipid-enveloped (NLE) types, which is perhaps of relevance for HEV clearance from manufacturing processes of antibody-containing PDMPs with solvent/detergent (S/D) therapy upstream of additional clearance steps.
Research design and strategies: Presence of various HEV particles in shares utilized in clearance research was investigated, with nanofilters graded across the assumed HEV particle sizes and by gradient centrifugation. HEV elimination by 35-nm nanofiltration was investigated within the presence or absence of HEV antibodies, in buffer in addition to in immunoglobulin (IG) manufacturing course of intermediates.
Outcomes: HEV particles in step with LE, NLE, and an “intermediate” (IM) phenotype, obtained after S/D therapy, have been seen in several HEV shares. Within the absence of HEV antibodies, log discount components (LRFs) of 4.Zero and a couple of.5 have been obtained by 35-nm nanofiltration of LE and IM HEV, in step with the bigger and smaller sizes of those phenotypes. Addition of HEV antibodies enhanced IM HEV elimination round 1000-fold (LRF, 5.6). Efficient (LRF, >4.eight and >4.0) HEV elimination was obtained for the nanofiltration processing step for IG intermediates with various HEV antibody content material.
Conclusion: HEV spikes utilized in clearance research ought to be fastidiously chosen, as variations in physicochemical properties would possibly have an effect on HEV clearance. Antibody-mediated enhancement of HEV nanofiltration was demonstrated in IG course of intermediates even at low HEV antibody focus, illustrating the robustness of this manufacturing step.
Antibody-protein binding and conformational modifications: figuring out allosteric signalling pathways to engineer a greater effector response
Quite a few monoclonal antibodies have been developed efficiently for the therapy of varied ailments. However, the event of biotherapeutic antibodies is advanced, costly, and time-consuming, and to facilitate this course of, cautious structural evaluation past the antibody binding website is required to develop a extra efficacious antibody.
- On this work, we targeted on protein antigens, since they induce the most important antibody modifications, and supply fascinating instances to check and distinction. The buildings of 15 anti-protein antibodies have been analysed to check the antigen-bound/unbound types.
- Surprisingly, three different courses of binding-induced modificationshave beenrecognized. In school (B1), the antigen binding fragment distorted considerably, and we discovered modifications within the loop area of the heavy chain’s fixed area; this corresponds nicely with anticipated allosteric actions. In school (B2), we discovered modifications in the identical loop area with out the general distortion.
- In school (B3), these modifications didn’t current, and solely local modificationson the complementarity figuring outareashave beendiscovered. Consequently, structural evaluation of antibodies is essential for therapeutic growth.
- Cautious analysis of allosteric actionshave to be undertaken to develop higher effector responses, particularly in the course of the transformation of those antibodies from small fragments on the discovery stage to full antibodies on the subsequent growth levels.
PSMB8 Antibody |
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1-CSB-PA775839 | Cusabio |
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Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
PSMB8 Antibody |
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E043134 | EnoGene | 100μg/100μl | EUR 255 |
Description: Available in various conjugation types. |
PSMB8 Antibody |
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1-CSB-PA018886GA01HU | Cusabio |
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Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF |
PSMB8 Antibody |
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1-CSB-PA018886LA01HU | Cusabio |
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Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
PSMB8 Antibody |
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E94054 | EnoGene | 100μg | EUR 255 |
Description: Available in various conjugation types. |
PSMB8 Antibody |
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E97340 | EnoGene | 100ul | EUR 255 |
Description: Available in various conjugation types. |
PSMB8 Antibody |
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E314816 | EnoGene | 100ug/200ul | EUR 295 |
Description: Available in various conjugation types. |
PSMB8 antibody |
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70R-13550 | Fitzgerald | 100 ul | EUR 550 |
Description: Affinity purified Rabbit polyclonal PSMB8 antibody |
PSMB8 antibody |
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70R-19589 | Fitzgerald | 50 ul | EUR 289 |
Description: Rabbit polyclonal PSMB8 antibody |
PSMB8 Antibody |
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1-CSB-PA116429 | Cusabio |
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Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
PSMB8 antibody |
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BF0434 | Nova Lifetech | 100ug | EUR 355 |
PSMB8 Antibody |
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MBS7113266-005mL | MyBiosource | 0.05mL | EUR 190 |
PSMB8 Antibody |
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MBS7113266-01mL | MyBiosource | 0.1mL | EUR 270 |
PSMB8 Antibody |
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MBS7113266-5x01mL | MyBiosource | 5x0.1mL | EUR 1205 |
PSMB8 Antibody |
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MBS7129229-005mL | MyBiosource | 0.05mL | EUR 190 |
PSMB8 Antibody |
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MBS7129229-01mL | MyBiosource | 0.1mL | EUR 270 |
PSMB8 Antibody |
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MBS7129229-5x01mL | MyBiosource | 5x0.1mL | EUR 1205 |
PSMB8 Antibody |
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MBS7129230-005mL | MyBiosource | 0.05mL | EUR 190 |
PSMB8 Antibody |
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MBS7129230-01mL | MyBiosource | 0.1mL | EUR 270 |
PSMB8 Antibody |
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MBS7129230-5x01mL | MyBiosource | 5x0.1mL | EUR 1205 |
PSMB8 antibody |
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MBS9405580-01mL | MyBiosource | 0.1mL | EUR 420 |
PSMB8 antibody |
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MBS9405580-5x01mL | MyBiosource | 5x0.1mL | EUR 1740 |
PSMB8 Antibody |
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MBS8500013-01mg | MyBiosource | 0.1mg | EUR 325 |
PSMB8 Antibody |
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MBS8500013-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
PSMB8 Antibody |
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MBS8500013-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
PSMB8 Antibody |
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MBS8500013-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
PSMB8 Antibody |
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MBS8500013-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
PSMB8 Antibody |
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MBS5312424-01mL | MyBiosource | 0.1mL | EUR 1070 |
PSMB8 Antibody |
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MBS5312424-5x01mL | MyBiosource | 5x0.1mL | EUR 4655 |
PSMB8 Antibody |
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MBS9416351-01mL | MyBiosource | 0.1mL | EUR 305 |
PSMB8 Antibody |
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MBS9416351-5x01mL | MyBiosource | 5x0.1mL | EUR 1230 |
PSMB8 Antibody |
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BF0434-100ul | Affinity Biosciences | 100ul | EUR 210 |
Description: WB,IHC,IF/ICC,ELISA |
PSMB8 Antibody |
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BF0434-200ul | Affinity Biosciences | 200ul | Ask for price |
Description: WB,IHC,IF/ICC,ELISA |
PSMB8 Antibody |
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BF0434-50ul | Affinity Biosciences | 50ul | EUR 150 |
Description: WB,IHC,IF/ICC,ELISA |
PSMB8 Conjugated Antibody |
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C43134 | SAB | 100ul | EUR 476.4 |
PSMB8 Polyclonal Antibody |
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E-AB-92394-120uL | Elabscience Biotech | 120uL | EUR 320 |
Description: Unconjugated |
PSMB8 Polyclonal Antibody |
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E-AB-92394-200uL | Elabscience Biotech | 200uL | EUR 530 |
Description: Unconjugated |
PSMB8 Polyclonal Antibody |
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E-AB-92394-60uL | Elabscience Biotech | 60uL | EUR 200 |
Description: Unconjugated |
PSMB8 Polyclonal Antibody |
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E-AB-92394-each | Elabscience Biotech | each | Ask for price |
Description: Unconjugated |
PSMB8 Polyclonal Antibody |
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A73468 | EpiGentek | 50 μl | EUR 557 |
PSMB8 Polyclonal Antibody |
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E-AB-61655-120uL | Elabscience Biotech | 120uL | EUR 320 |
Description: Unconjugated |
PSMB8 Polyclonal Antibody |
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E-AB-61655-200uL | Elabscience Biotech | 200uL | EUR 530 |
Description: Unconjugated |
PSMB8 Polyclonal Antibody |
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E-AB-61655-60uL | Elabscience Biotech | 60uL | EUR 200 |
Description: Unconjugated |
PSMB8 Polyclonal Antibody |
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E-AB-61655-each | Elabscience Biotech | each | Ask for price |
Description: Unconjugated |
PSMB8 Polyclonal Antibody |
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MBS2538339-006mL | MyBiosource | 0.06mL | EUR 190 |
PSMB8 Polyclonal Antibody |
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MBS2538339-012mL | MyBiosource | 0.12mL | EUR 265 |
PSMB8 Polyclonal Antibody |
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MBS2538339-02mL | MyBiosource | 0.2mL | EUR 415 |
PSMB8 Polyclonal Antibody |
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MBS2538339-5x02mL | MyBiosource | 5x0.2mL | EUR 1835 |
PSMB8 Polyclonal Antibody |
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MBS2527805-002mL | MyBiosource | 0.02mL | EUR 140 |
PSMB8 Polyclonal Antibody |
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MBS2527805-006mL | MyBiosource | 0.06mL | EUR 180 |
PSMB8 Polyclonal Antibody |
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MBS2527805-012mL | MyBiosource | 0.12mL | EUR 260 |
PSMB8 Polyclonal Antibody |
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MBS2527805-02mL | MyBiosource | 0.2mL | EUR 405 |
PSMB8 Polyclonal Antibody |
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MBS2527805-5x02mL | MyBiosource | 5x0.2mL | EUR 1725 |
PSMB8 Polyclonal Antibody |
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MBS2528965-002mL | MyBiosource | 0.02mL | EUR 140 |
PSMB8 Polyclonal Antibody |
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MBS2528965-006mL | MyBiosource | 0.06mL | EUR 180 |
PSMB8 Polyclonal Antibody |
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MBS2528965-012mL | MyBiosource | 0.12mL | EUR 260 |
PSMB8 Polyclonal Antibody |
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MBS2528965-02mL | MyBiosource | 0.2mL | EUR 405 |
PSMB8 Polyclonal Antibody |
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MBS2528965-5x02mL | MyBiosource | 5x0.2mL | EUR 1725 |
PSMB8 Conjugated Antibody |
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MBS9451453-01mLAF350 | MyBiosource | 0.1mL(AF350) | EUR 480 |
PSMB8 Conjugated Antibody |
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MBS9451453-01mLAF405 | MyBiosource | 0.1mL(AF405) | EUR 480 |
PSMB8 Conjugated Antibody |
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MBS9451453-01mLAF488 | MyBiosource | 0.1mL(AF488) | EUR 480 |
PSMB8 Conjugated Antibody |
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MBS9451453-01mLAF555 | MyBiosource | 0.1mL(AF555) | EUR 480 |
PSMB8 Conjugated Antibody |
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MBS9451453-01mLBiotin | MyBiosource | 0.1mL(Biotin) | EUR 480 |
PSMB8 Polyclonal Antibody |
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RD84433A-120uL | Reddot Biotech | 120μL | EUR 360 |
Description: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. |
PSMB8 Polyclonal Antibody |
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RD84433A-200uL | Reddot Biotech | 200μL | EUR 630 |
Description: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. |
PSMB8 Polyclonal Antibody |
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RD84433A-60uL | Reddot Biotech | 60μL | EUR 204 |
Description: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. |
PSMB8 Antibody (N-term) |
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MBS9213569-008mL | MyBiosource | 0.08mL | EUR 210 |
PSMB8 Antibody (N-term) |
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MBS9213569-04mL | MyBiosource | 0.4mL | EUR 430 |
PSMB8 Antibody (N-term) |
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MBS9213569-5x04mL | MyBiosource | 5x0.4mL | EUR 1910 |
PSMB8 Antibody, HRP conjugated |
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1-CSB-PA018886LB01HU | Cusabio |
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Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
PSMB8 Antibody, HRP Conjugated |
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MBS7113267-005mL | MyBiosource | 0.05mL | EUR 190 |
PSMB8 Antibody, HRP Conjugated |
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MBS7113267-01mL | MyBiosource | 0.1mL | EUR 270 |
PSMB8 Antibody, HRP Conjugated |
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MBS7113267-5x01mL | MyBiosource | 5x0.1mL | EUR 1205 |
PSMB8 Antibody, FITC conjugated |
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1-CSB-PA018886LC01HU | Cusabio |
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Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
OACD05288-1ML - PSMB8 Antibody |
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OACD05288-1ML | Aviva Systems Biology | 1ml | EUR 649 |
OACD05289-1ML - PSMB8 Antibody |
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OACD05289-1ML | Aviva Systems Biology | 1ml | EUR 659 |
OACD05290-1ML - PSMB8 Antibody |
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OACD05290-1ML | Aviva Systems Biology | 1ml | EUR 639 |
PSMB8 Antibody, FITC Conjugated |
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MBS7113268-005mL | MyBiosource | 0.05mL | EUR 190 |
PSMB8 Antibody, FITC Conjugated |
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MBS7113268-01mL | MyBiosource | 0.1mL | EUR 270 |
PSMB8 Antibody, FITC Conjugated |
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MBS7113268-5x01mL | MyBiosource | 5x0.1mL | EUR 1205 |
OAAN02231-50UL - PSMB8 Antibody |
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OAAN02231-50UL | Aviva Systems Biology | 50ul | EUR 149 |
PSMB8 Antibody, Biotin conjugated |
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1-CSB-PA018886LD01HU | Cusabio |
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Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
OACD05288-100UL - PSMB8 Antibody |
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OACD05288-100UL | Aviva Systems Biology | 100ul | EUR 199 |
OACD05289-100UL - PSMB8 Antibody |
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OACD05289-100UL | Aviva Systems Biology | 100ul | EUR 189 |
OACD05290-100UL - PSMB8 Antibody |
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OACD05290-100UL | Aviva Systems Biology | 100ul | EUR 189 |
OAAN02231-100UL - PSMB8 Antibody |
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OAAN02231-100UL | Aviva Systems Biology | 100ul | EUR 249 |
OAAN02231-200UL - PSMB8 Antibody |
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OAAN02231-200UL | Aviva Systems Biology | 200ul | EUR 389 |
OAEB02189-100UG - PSMB8 Antibody |
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OAEB02189-100UG | Aviva Systems Biology | 100ug | EUR 349 |
OAGA01026-100UL - PSMB8 antibody |
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OAGA01026-100UL | Aviva Systems Biology | 100ul | EUR 369 |
PSMB8 Antibody, Biotin Conjugated |
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MBS7113269-005mL | MyBiosource | 0.05mL | EUR 190 |
PSMB8 Antibody, Biotin Conjugated |
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MBS7113269-01mL | MyBiosource | 0.1mL | EUR 270 |
PSMB8 Antibody, Biotin Conjugated |
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MBS7113269-5x01mL | MyBiosource | 5x0.1mL | EUR 1205 |
Human, Rat, Mouse PSMB8 antibody |
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P0987 | Omnimabs | 100ul | EUR 150 |
PSMB8 Rabbit Polyclonal Antibody |
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55187 | SAB | 100ul | EUR 439 |
PSMB8 Rabbit Polyclonal Antibody |
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E10G05021 | EnoGene | 100 μl | EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
PSMB8 Rabbit Polyclonal Antibody |
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E10G11908 | EnoGene | 100 μl | EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
PSMB8 Rabbit Polyclonal Antibody |
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MBS9466218-005mL | MyBiosource | 0.05mL | EUR 300 |
Antibody profiling of a Borreliella burgdorferi (Lyme illness) C6 antibody optimistic, symptomatic Rottweiler and her pups
Lyme illness (LD) is a tick-transmitted illness attributable to Borreliella burgdorferi (Bb). Temporal research of maternal antibody (Ab) profiles in Bb contaminated pregnant canine and their pups haven’t been performed. On this research, Ab profiles of a client-owned Bb C6 Ab optimistic Rottweiler and her 9 pups have been assessed.
The dam introduced with lameness 12 days previous to parturition and was C6 Ab optimistic with a Quant C6 Ab focus of 237U/mL. Therapy with amoxicillin was initiated and 11 days later 9 pups have been delivered. Screening of the sera from the dam and pups towards Bb cell lysates and a panel of antigens revealed related immunoreactivity profiles.
Whereas antigen-specific IgG and IgM reactivity continued within the dam for at the least 7 months, a fast decline in IgG particular for BBA36, BBK53, BB0238, BBA73 and outer floor protein (Osp) E within the pups occurred between days 29 and 52 post-parturition. In distinction, Ab particular for DbpA and the diagnostic antigens VlsE (C6) and OspF, remained elevated within the pups.
Sera from the dam displayed potent complement-dependent bactericidal exercise towards Bb. Sera from the pups was additionally bactericidal however primarily by means of a complement-independent mechanism. Lastly, single dose vaccination of the dam at day 51 post-parturition with a LD subunit vaccine consisting of OspA and an OspC chimeritope triggered a broad anti-OspC Ab response indicative of an anamnestic response. Though this research targeted on a single case, these findings add to our data of maternal Ab profiles and can help the interpretation of serological assays in pups delivered by a Bb C6 Ab optimistic canine.
Human Resistin |
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90233-A | BPS Bioscience | 5 µg | EUR 130 |
Description: Recombinant Resistin is a disulfide-linked homodimeric protein consisting of two 93 amino acid residues, and migrates as an approximately 20 kDa protein under non-reducing conditions and as a 10 kDa protein under reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Resistin mature chain was expressed in E. coli. |
Human Resistin |
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90233-B | BPS Bioscience | 25 µg | EUR 205 |
Description: Recombinant Resistin is a disulfide-linked homodimeric protein consisting of two 93 amino acid residues, and migrates as an approximately 20 kDa protein under non-reducing conditions and as a 10 kDa protein under reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Resistin mature chain was expressed in E. coli. |
Human Resistin |
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MBS692069-0005mg | MyBiosource | 0.005mg | EUR 300 |
Human Resistin |
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MBS692069-0025mg | MyBiosource | 0.025mg | EUR 450 |
Human Resistin |
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MBS692069-5x0025mg | MyBiosource | 5x0.025mg | EUR 1725 |
Human resistin |
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MBS400069-001mg | MyBiosource | 0.01mg | EUR 220 |
Human resistin |
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MBS400069-005mg | MyBiosource | 0.05mg | EUR 545 |
Human resistin |
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MBS400069-01mg | MyBiosource | 0.1mg | EUR 770 |
Human resistin |
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MBS400069-1mg | MyBiosource | 1mg | EUR 3830 |
Human Resistin Antibody |
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32138-05111 | AssayPro | 150 ug | EUR 215 |
Human Resistin Antibody |
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GWB-F7AAE4 | GenWay Biotech | 0.1 mg | Ask for price |
Resistin (43-65) (Human) - Antibody |
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H-028-39 | PHOENIX PEPTIDE | 50 μl | EUR 604.8 |
Resistin (51-108) (Human) - Antibody |
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H-028-40 | PHOENIX PEPTIDE | 50 μl | EUR 604.8 |
Resistin (43-65) (Human) |
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028-39 | PHOENIX PEPTIDE | 100 μg | EUR 255.96 |
Resistin (51-108) (Human) |
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028-40 | PHOENIX PEPTIDE | 20 μg | EUR 282.96 |
Resistin (23-42) (Human) |
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028-41 | PHOENIX PEPTIDE | 100 μg | EUR 214.92 |
Resistin (25-42) (Human) |
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028-42 | PHOENIX PEPTIDE | 100 μg | EUR 214.92 |
Mouse Anti-Human Resistin |
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MBS690775-05mg | MyBiosource | 0.5mg | EUR 525 |
Mouse Anti-Human Resistin |
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MBS690775-5x05mg | MyBiosource | 5x0.5mg | EUR 2080 |
Anti-Human Resistin Antibody |
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101-M170 | ReliaTech | 500 µg | EUR 246.75 |
Description: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant human Resistin is a 19.5 kDa disulfide-linked homodimeric protein composed of two identical 92 amino acid chains linked by a single disulfide bond. |
Anti-Human Resistin Antibody |
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101-M618 | ReliaTech | 100 µg | EUR 399 |
Description: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. |
Anti-Human Resistin Antibody |
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102-P92G | ReliaTech | 100 µg | EUR 245.7 |
Description: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. |
Human Resistin (RETN) |
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1-CSB-EP019573HU | Cusabio |
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Description: Recombinant Human Resistin(RETN) expressed in E.coli |
Human resistin antagonist |
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MBS400115-001mg | MyBiosource | 0.01mg | EUR 220 |
Human resistin antagonist |
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MBS400115-005mg | MyBiosource | 0.05mg | EUR 545 |
Human resistin antagonist |
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MBS400115-01mg | MyBiosource | 0.1mg | EUR 770 |
Human resistin antagonist |
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MBS400115-1mg | MyBiosource | 1mg | EUR 3830 |
Biotinylated Anti-Human Resistin |
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GWB-BIG87D | GenWay Biotech | 1 kit | Ask for price |
Recombinant Human Resistin |
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7-01519 | CHI Scientific | 5µg | Ask for price |
Recombinant Human Resistin |
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7-01520 | CHI Scientific | 25µg | Ask for price |
Recombinant Human Resistin |
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7-01521 | CHI Scientific | 1mg | Ask for price |
RECOMBINANT HUMAN RESISTIN |
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GWB-F4A137 | GenWay Biotech | 0.02 mg | Ask for price |
Recombinant Human Resistin |
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cyt-456-1mg | ProSpec Tany | 1mg | EUR 4680 |
Recombinant Human Resistin |
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cyt-456-25g | ProSpec Tany | 25µg | EUR 145 |
Recombinant Human Resistin |
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cyt-456-5g | ProSpec Tany | 5µg | EUR 60 |
Recombinant Human Resistin |
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MBS7611410-005mg | MyBiosource | 0.05mg | EUR 345 |
Recombinant Human Resistin |
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MBS7611410-02mg | MyBiosource | 0.2mg | EUR 635 |
Recombinant Human Resistin |
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MBS7611410-1mg | MyBiosource | 1mg | EUR 1800 |
Recombinant Human Resistin |
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MBS7611410-5x1mg | MyBiosource | 5x1mg | EUR 6955 |
Recombinant Human Resistin |
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MBS142332-0005mg | MyBiosource | 0.005mg | EUR 240 |
Recombinant Human Resistin |
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MBS142332-0025mg | MyBiosource | 0.025mg | EUR 310 |
Recombinant Human Resistin |
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MBS142332-1mg | MyBiosource | 1mg | EUR 4895 |
Recombinant Human Resistin |
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MBS142332-5x1mg | MyBiosource | 5x1mg | EUR 21695 |
Recombinant Human Resistin |
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MBS1410331-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 255 |
Recombinant Human Resistin |
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MBS1410331-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 405 |
Recombinant Human Resistin |
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MBS1410331-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 1425 |
Recombinant Human Resistin |
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MBS1410331-5x1mgEColi | MyBiosource | 5x1mg(E-Coli) | EUR 6215 |
RECOMBINANT HUMAN RESISTIN |
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MBS232425-0025mg | MyBiosource | 0.025mg | EUR 510 |
RECOMBINANT HUMAN RESISTIN |
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MBS232425-5x0025mg | MyBiosource | 5x0.025mg | EUR 2130 |
Human Resistin Recombinant |
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MBS553192-0005mg | MyBiosource | 0.005mg | EUR 165 |
Human Resistin Recombinant |
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MBS553192-0025mg | MyBiosource | 0.025mg | EUR 245 |
Recombinant Human Resistin |
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MBS9420612-002mg | MyBiosource | 0.02mg | EUR 285 |
Recombinant Human Resistin |
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MBS9420612-01mg | MyBiosource | 0.1mg | EUR 470 |
Recombinant Human Resistin |
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MBS9420612-1mg | MyBiosource | 1mg | EUR 1785 |
Recombinant Human Resistin |
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MBS9420612-5x1mg | MyBiosource | 5x1mg | EUR 7885 |
Human Resistin CLIA Kit |
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MBS8425884-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Resistin, human recombinant |
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4559-100 | Biovision | each | EUR 874.8 |
Resistin, human recombinant |
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4559-1000 | Biovision | each | EUR 6127.2 |
Resistin, human recombinant |
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4559-25 | Biovision | each | EUR 307.2 |
Resistin (Recombinant) Human |
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GWB-8EE40A | GenWay Biotech | 0.025 mg | Ask for price |
Resistin, recombinant (Human) |
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028-36 | PHOENIX PEPTIDE | 20 μg | EUR 423.36 |
Resistin Human Recombinant |
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rAP-0727 | Angio Proteomie | Inquiry | Ask for price |
Human Resistin ELISA kit |
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E01R0351-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Human Resistin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Resistin ELISA kit |
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E01R0351-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Human Resistin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Resistin ELISA kit |
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E01R0351-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Human Resistin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Resistin ELISA kit |
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E01A7519 | BlueGene | 96T | EUR 700 |
Description: ELISA |
Human Resistin ELISA Kit |
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E16HE0035 | EnoGene | 96T | EUR 833.33 |
Human Resistin ELISA KIT |
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E16HE0035-048 | EnoGene | 48 wells | EUR 295 |
Human Resistin ELISA KIT |
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E16HE0035-096 | EnoGene | 96 wells | EUR 395 |
Human Resistin ELISA KIT |
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EKC40240-48T | Biomatik Corporation | 48T | EUR 412.02 |
Human Resistin ELISA KIT |
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EKC40240-5x96T | Biomatik Corporation | 5x96T | EUR 2795.85 |
Human Resistin ELISA KIT |
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EKC40240-96T | Biomatik Corporation | 96T | EUR 588.6 |
Human Resistin ELISA KIT |
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E42EH-93 | EnoGene | 96T/48T | Ask for price |
Human Resistin ELISA kit |
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E22-HC136.48 | EnoGene | 48T | EUR 295 |
Human Resistin ELISA kit |
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E22-HC136.96 | EnoGene | 96T | EUR 395 |
Human Resistin ELISA Kit |
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E28L0045 | EnoGene | 96T | EUR 666.67 |
Human Resistin ELISA Kit |
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EK2351 | SAB | 96 tests | EUR 497 |
Human Resistin ELISA Kit |
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EHR0358 | Abclonal | 96Tests | EUR 625.2 |